Searchable abstracts of presentations at key conferences in endocrinology

ea0009p86 | Endocrine tumours and neoplasia | BES2005

Adiponectin receptor expression in human prostate cancer cell lines

Mistry T , Karteris E , Digby J , Chen J , Desai K , Randeva H

Adiponectin has been shown to modulate angiogenesis and tumour cell behaviour. Breast and endometrial cancer patients have significantly decreased serum adiponectin levels, which may be important in such hormone-dependent cancers. Prostate cancer is another hormone-dependent cancer. Adiponectin orchestrates its actions by activating two seven-transmembrane receptors, adiponectin-R1 (adipo-R1) and adiponectin-R2 (adipo-R2). In this study we aim to determine adipo-R1/R2 expressi...